Fluorescence Correlation Spectroscopy Measurement Based on Fiber Optics for Biological Materials

A robust fluorescence correlation spectroscopy system called fiber-optic based (FB-FCS) was developed; this enables the measurement of diffusion dynamics and concentration fluorescent molecules on principle without any mechanical adjustment experimental setup. The consisted fiber optics a water-immersion objective lens. hydrodynamic diameters concentrations organic dyes fluorescently labeled proteins were successfully measured. Because fiber-optic-based setup, FB-FCS is compact inexpensive. We expect to be suitable for use in laboratories, medical diagnosis, environmental measurements.